Systems Biology

Mission

Our mission is to understand the structure and function of living systems at all levels, from molecules to ecosystems. At the level of ecosystems, we seek to understand how living ecosystems arise from complex sets of interactions between organisms and with their environment. On increasingly smaller physical scales, we seek to understand how living organisms arise from complex systems of interacting cells, and how living cells arise from complex networks of interacting macromolecules and reactions. At the smallest physical scale, we seek to understand how macromolecular structure and function emerge from complex interactions among the atoms of a macromolecule and between these atoms and their molecular environment.

Our mission requires both new ideas and also new data and novel analysis methods. Consequently, two important components of our work focus on developing and applying new experimental methods to obtain the facts and systems engineering and network theory methods for the integration and analysis of these facts on which our larger , systems quantitative understanding will be based.

Directors

Vassily Hatzimanikatis, vassily@northwestern.edu
http://systemsbiology.northwestern.edu

Richard I. Morimoto, r-morimoto@northwestern.edu
www.biochem.northwestern.edu/ibis/morimoto/morimoto_home.html

Affiliated Faculty

Luis Amaral, amaral@northwestern.edu
http://amaral.northwestern.edu/

Gary Borisy, g-borisy@northwestern.edu
http://www.borisylab.northwestern.edu/

Thomas J. Meade, tmeade@northwestern.edu
www.chem.northwestern.edu/%7Etmeade/

E. Terry Papoutsakis, e-paps@northwestern.edu
www.papoutsakisresearch.northwestern.edu/

Olke C. Uhlenbeck, o-uhlenbeck@northwestern.edu
www.biochem.northwestern.edu/ibis/faculty/uhlenbeck.htm

Eric Weiss, elweiss@northwestern.edu
www.biochem.northwestern.edu/ibis/faculty/weiss.htm

Jonathan Widom, j-widom@northwestern.edu
www.biochem.northwestern.edu/widomweb/index.html