January 12, 2009 | Commentary

Brain Starvation as We Age Appears to Trigger Alzheimer’s

By Megan Fellman
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CHICAGO --- A slow, chronic starvation of the brain as we age appears to be one of the major triggers of a biochemical process that causes some forms of Alzheimer's disease.

A new study from Northwestern University's Feinberg School of Medicine has found when the brain doesn't get enough sugar glucose -- as might occur when cardiovascular disease restricts the blood flow in arteries to the brain -- a process is launched that ultimately produces the sticky clumps of protein that appear to be a cause of Alzheimer's.

Robert Vassar, lead author and a professor of cell and molecular biology, discusses the study and Alzheimer's disease

Megan Fellman is the science and engineering editor. Contact her at fellman@northwestern.edu

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