CHICAGO --- Teepu Siddique, M.D., professor of neurology and of cell and molecular biology, has been named the first Les Turner ALS Foundation/Herbert C. Wenske Professor at the Northwestern University Feinberg School of Medicine.
Siddique is director of the Northwestern University Neuromuscular Disorders Program.
Siddique’s laboratory studies disorders of the human neurodegeneration, focusing on the prototypic neurodegenerative disorders of the upper and lower motor neuron, such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophies and familial spastic paraplegias.
He headed the team that first identified the gene responsible for ALS, also known as Lou Gehrig’s disease, and developed the first animal model – the first major advances in ALS research in 125 years.
Siddique and his colleagues also identified a second gene mutation that is responsible for a rare, slowly progressive, early-onset form of the disease, called juvenile inherited ALS, discovered in highly inbred populations in North Africa and the Middle East.
Siddique’s studies have been funded by grants from the National Institutes of Health, Les Turner ALS Foundation, Grant Healthcare Foundation, Michael Jordan Foundation and Ralph and Marian Falk Medical Research Trust.
His work has been published in many journals including Neurology, Journal of Neurophysiology and Human Genetics.
Before joining Northwestern in 1991, Siddique was on faculty at the University of Southern California, followed by six years of service at Duke University.