Systems and cognitive neuroscience; sensorimotor integration; selection and control of eye movements in primates

The generation of eye movements is an important function of the brain's control systems. My laboratory uses the eye movement system as a model for how the brain of primates, including man, controls a variety of movements. Our work focuses upon areas of the rhesus monkey's prefrontal cortex and midbrain that help to control eye movements. We use behavioral and neurophysiological techniques in awake, behaving monkeys to allow us to examine the processing of information taking place within these areas, and to enable us to understand the role these neural structures perform in the complex network of connections that make up the oculomotor system.

e-mail Dr. Segraves
ph: 847.491.5072
fax: 847.491.5211

Selected References:

• Ratcliff R, Hasegawa YT, Hasegawa RP, Smith PL, Segraves MA. (2007). Dual diffusion model for single-cell recording data from the superior colliculus in a brightness-discrimination task. J Neurophysiol. 97(2):1756-74.

• Hasegawa RP, Hasegawa YT, Segraves MA. (2006). Single trial-based prediction of a go/no-go decision in monkey superior colliculus. Neural Netw. 19(8):1223-32.

• Farrell S, Ratcliff R, Cherian A, Segraves M. (2006). Modeling unidimensional categorization in monkeys. Learn Behav. 34(1):86-101.

• Campos M, Cherian A, Segraves MA. (2006). Effects of eye position upon activity of neurons in macaque superior colliculus. J Neurophysiol. 95(1):505-26.

• Ratcliff R, Cherian A, Segraves M (2003). A comparison of macaque behaviorand superior colliculus neuronal activity to predictions from models oftwo-choice decisions. J Neurophysiol 90:1392-1407.

• Helminski JO, Segraves MA (2003). Macaque frontal eye field input tosaccade-related neurons in the superior colliculus. J Neurophysiol90:1046-1062.

Other Links:

• Society for Neuroscience