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Mark
Segraves |
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Systems and cognitive neuroscience; sensorimotor integration; selection and control of eye movements in primates The generation of eye movements is an important function of the brain's control systems. My laboratory uses the eye movement system as a model for how the brain of primates, including man, controls a variety of movements. Our work focuses upon areas of the rhesus monkey's prefrontal cortex and midbrain that help to control eye movements. We use behavioral and neurophysiological techniques in awake, behaving monkeys to allow us to examine the processing of information taking place within these areas, and to enable us to understand the role these neural structures perform in the complex network of connections that make up the oculomotor system. |
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Associate
Professor PhD, Pennsylvania |
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e-mail
Dr. Segraves |
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| Selected References: • Ratcliff R, Cherian A, Segraves M (2003) A comparison of macaque behaviorand superior colliculus neuronal activity to predictions from models oftwo-choice decisions. J Neurophysiol 90:1392-1407. • Helminski JO, Segraves MA (2003) Macaque frontal eye field input tosaccade-related neurons in the superior colliculus. J Neurophysiol90:1046-1062. •Dias EC, Segraves MA (1999) Muscimol-induced inactivation of monkeyfrontal eye field: effects on visually and memory-guided saccades. JNeurophysiol 81:2191-2214. • Dias, E. C., M. Kiesau, and M. A. Segraves (1995)
Acute activation and inactivation of macaque frontal eye field with GABA-related
drugs.
Journal of Neurophysiology 74: 2744-2748. |
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