Kreeger PK, Woodruff TK, Shea LD.  Murine granulose cell morphology and function are regulated by a synthetic Arg-Gly-Asp matrix.  Mol Cell Endocrinol. 2003 205(1-2): 1-10. 

Pangas SA, Saudye H, Shea L, Woodruff TK, Novel approach for the three-dimensional culture of granulose cell-oocyte complexes.  Tissue Eng. 2003 9(5):1013-21.

Thompson TB, Woodruff TK, Jardetzky TS. Structures of an Act RIIB: activin A complex reveal a novel binding mode for TGF-beta ligand: receptor interactions. EMBO J. 2003 Apr; 1;22(7):1555-66.

Thompson TB, Cook RW, Chapman SC, Jardetzky TS, Woodruff TK.  Beta A versus Beta B: is it merely a matter of expression?  Mol Cell Endocrinol.  2004 Oct; 15; 255 (1-2):9-17.

Cook RW, Thompson, TB, Jardetzky TS, Woodruff TK.  Molecular biology of inhibin action.  Semin Reprod Med. 2004 Aug; 22(3):269-76. Review.

Thompson TB, Cook RW, Chapman SC, Jardetzky TS, Woodruff TK. Beta A versus beta B: is it merely a mater of expression?  Mol Cell Endocrinol. 2004 Oct; 15;22(1-2):9-17. Review.

Zhang X, Jafari N, Barnes RB, Confino E, Milad M, Kazer RR.  Studies of gene expression in human cumulus cells indicate pentraxin 3 as a possible marker for oocyte quality.  Fertil Steril. 2005 Apr; 83 Suppl 1:1169-79.

Burkart AD, Mukherjee A, Sterneck E, Johnson PF, Mayo KE.  Repression of the inhibin alpha-subunit gene by the transcription factor CCAAT/enhancer-binding protein-beta.  Endocrinology. 2005 Apr; 146(4):1909-21.

Kreeger PK, Fernandes NN, Woodruff TK, Shea LD.  Regulation of mouse follicle development by follicle-stimulating hormone in a three-dimensional in vitro culture system is dependent on follicle stage and dose.  Biol Reprod. 2005 Nov; 73(5):942-40.

Cook RW, Thompson TB, Kurup SP, Jardetzky TS, Woodruff TK.  Structural basis for a functional antagonist in the transforming growth factor beta superfamily.  J Biol Chem. 2005 Dec; 2:280(48):40177-86.

Thompson TB, Lerch TF, Cook RW, Woodruff TK, Jardetzky T S.  The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding.  Dev Cell. 2005 Oct; 9(4):535-43.

Hunzicker-Dunn M, Mayo K. Gonadotropin Signaling in the Ovary. In: Knobil E, Neill JD (eds.), The Physiology of Reproduction. 3rd ed. New York: Academic Press; 2005.

Zhang X, Jafari N,Barnes RB, Confino E, Milad M, Kazer RR. Studies of gene expression in human cumulus cells indicate pentraxin 3 as a possible marker for oocyte quality. Ferti Steril. 2005 Apr; 83 Suppl 1:1169-79.

Kreeger PK, Deck JW, Woodruff TK, Shea LD.  The in vitro regulation of ovarian follicle development using alginate-extracellular matrix gels.  Biomaterials. 2006 Feb; 27(5):714-23.

Nieman CL, Kazer R, Brannigan RE, Zoloth LS, Chase-Landsdale PL, Kinahan K, Dilley KJ, Roberts D, Shea LD, Woodruff TK.  Cancer survivors and infertility: a review of a new problem and novel answers.  J Support Oncol. 2006 Apr; 4(4):171-8.

Berkholtz CB, Lai BE, Woodruff TK, Shea LD.  Distribution of extracellular matrix proteins type I collagen, type IV collagen, fibraonetction, and laminin in mouse folliculogenesis. Histochem Cell Biol. 2006 Jun 7; [Epub ahead of print].

Xu M, Kreeger PK, Shea LD, Woodruff TK.  Tissue-engineered follicles produce live, fertile offspring.  Tissue Eng. 2006 Jun 1; [Epub ahead of print].

Weck J, Mayo KE. Switching of NR5A Proteins Associated with the Inhibin alpha-Subunit Gene Promoter after Activation of the Gene in Granulosa Cells. Mol Endocrinol. 2006 20(5):1090-1103.

Little TH, Zhang Y, Matulis CK, Weck J, Zhang Z, Ramachandran A, Mayo KE, Radhakrishnan I. Sequence-Specific Deoxyribonucleic Acid (DNA) Recognition by Steroidogenic Factor 1: A Helix at the Carboxy Terminus of the DNA Binding Domain Is Necessary for Complex Stability. Mol Endocrinol. 2006 20(4):831-843.

Burkart AD, Mukherjee A, Mayo KE. Mechanism of Repression of the Inhibin alpha-Subunit Gene by Inducible 3', 5'-Cyclic Adenosine Monophosphate Early Repressor. Mol Endocrinol. 2006 20(3):584-597.

Lin SJ, Lerch TF, Cook RW, Jardetzky TS, Woodruff TK. The structural basis of TGF-beta, bone morphogenetic protein, and activin ligand binding. Reproduction. 2006 Aug;132(2):179-90. Review. 

Xu M, West E, Shea LD, Woodruff TK. Identification of a stage-specific permissive in vitro culture environment for follicle growth and oocyte development. Biol Reprod. 2006 Dec;75(6):916-23.

Berkholtz CB, Shea LD, Woodruff TK. Extracellular matrix functions in follicle maturation. Semin Reprod Med. 2006 Sep;24(4):262-9. Review.

Bristol-Gould SK, Kreeger PK, Selkirk CG, Kilen SM, Cook RW, Kipp JL, Shea LD, Mayo KE, Woodruff TK. Postnatal regulation of germ cells by activin: the establishment of the initial follicle pool. Dev Biol. 2006 Oct 1;298(1):132-48.

Bristol-Gould SK, Kreeger PK, Selkirk CG, Kilen SM, Mayo KE, Shea LD, Woodruff TK. Fate of the initial follicle pool: empirical and mathematical evidence supporting its sufficiency for adult fertility. Dev Biol. 2006 Oct 1;298(1):149-54.

Lerch TF, Xu M, Jardetzky TS, Mayo KE, Radhakrishnan I, Kazer R, Shea LD, Woodruff TK. At the cutting edge: The structures that underlie normal reproductive function. Mol Cell Endocrinol. 2006 Nov 2.

Reconstructed Basement Membrane Regulation of Murine Follicle Maturation in a Three-Dimensional Culture System (Kreeger P, Deck J, Fernandes N, Woodruff TK, Shea L)

Gonadotrophin Supplementation Enhances Development for Murine Preantral Follicles in a Three Dimensional System (Kreeger P, Fernandes N, Berkholtz C, Woodruff TK, Shea L)

A Novel Three-Dimensional System for the in vitro Culture of Immature Murine Ovarian Follicles (Kreeger P, Berkholtz C, Woodruff TK, Shea L)

Alginate Matrices for the Culture of Immature Murine Ovarian Follicles (Kreeger P, Berkholtz C, Woodruff TK, Shea L)

In Vitro Maturation of Granulosa-Oocyte Complexes in Synthetic Scaffolds (Kreeger P, Berkholtz C, Woodruff TK, Shea L)

A Novel System for in vitro Culture of Immature Granulosa-Oocyte Complexes (Kreeger P, Berkholtz C, Woodruff TK, Shea L)

Alginate Matrices to Regulate Granulosa Cell Morphology and Steroid Production (Kreeger P, Woodruff TK, Shea L)

Synthetic Scaffolds to Regulate Granulosa Cell Adhesion and Spreading (Kreeger P, Woodruff TK, Shea L)

Center For Reproductive Research at Northwestern University 2205 Tech Drive, Hogan 2-160 Evanston, IL 60208

Ph: (847) 491-3627 Fax: (847) 491-2224 b-cushing@northwestern.edu