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email: |
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http://www.bme.northwestern.edu/faculty_staff/core/johnson.php |
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(847)467-7143 |
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Biomedical
Engineering Department |
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Education
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B.S. (Interdisciplinary Engineering)
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Purdue, 1975
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B.S. (Mathematics)
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Purdue, 1975
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S.M. (Mechanical Engineering)
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M.I.T., 1981
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Ph.D. (Mechanical Engineering)
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M.I.T., 1987
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Experience
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Powers Regulator Co.
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Computer Programmer (summer 1974)
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Argonne National Lab.
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Research Assistant (summer 1975)
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TRW Inc.
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Test Engineer (1975-1977)
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Pratt & Whitney Aircraft
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Design Engineer (1977-1979)
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MIT
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Research Engineer (1981-1985)
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Mass. Eye & Ear Infirmary
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Research Associate (1984-1991)
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MIT
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Instructor (Fall 1986)
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Harvard Medical School
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Associate in Ophthalmol. (1986-1988)
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MIT
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Research Engineer (1987-1990)
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Harvard Medical School
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Instructor in Ophthalmol. (1988-1991)
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MIT
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Principal Research Engineer (1990-1999)
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Tsongas Committee
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Mid-Atlantic Coordinator (winter 1991-1992)
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MIT
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Asst. MIT Varsity Squash Coach (1995-1998)
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Northwestern University
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Associate Professor (2000 to present)
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Northwestern University
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NU Squash Club Coach (2001 to present)
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Personal
Interests
squash, tennis, skiing, fishing, wild mushrooms, wild plants, fine wines,
wine making, hiking, politics, camping
Research
Interests
cause of glaucoma, cellular mechanics, transport through connective tissues,
nanoscale biotransport, macromolecular transport, physiochemical hydrodynamics,
cause of age-related macular degeneration, morphometric analysis, ocular bioengineering,
relationship between chaos and diffusion, lung surfactant
PUBLICATIONS
Chapters:
1. Johnson, M. and
Erickson, K.: Mechanisms and routes of aqueous humor drainage. Principles
and Practice of Ophthalmology ,Volume
I: Basic Sciences, chapter 11B, Ed. Albert , D.M. and Jakobiec, F.A., WB Saunders
Co. Philadelphia, 2000.
2. Johnson, D. and
Johnson, M.: How does non-penetrating glaucoma surgery work?, Non-Penetrating
Glaucoma Surgery, chapter 4, Ed. Mermoud,
A. and Shaarawy, T., Martin Dunitz, Ltd., London, 2001 (reprinted from Journal
of Glaucoma).
Papers:
1. Johnson,M.: Turbulent
heat transfer to a rotating disk: a review and extension of Dorfman. ASME
Journal of Heat Transfer, Nov 1980, 780-1.
2. Johnson,M. and
Kamm,R.D.: The role of Schlemm's canal
in aqueous outflow from the human eye. Investigative Ophthalmology
and Visual Science 24: 320-5, 1983.
3. Johnson,M., Ethier,C.R., Kamm,R.D., Grant,W.M., Epstein,D.E. and Gaasterland,D.: The flow of aqueous humor through micro-porous filters. Investigative Ophthalmology and Visual Science 27: 92-7, 1986.
4. Kamm,R.D., Butcher,R., Froelich,J., Johnson,M., Salzman,E., Shapiro,A.
and Strauss,H.W.: Optimization of parameters
of external pneumatic compression for prophylaxis against deep vein thr ombosis:
radionuclide gated imaging studies. Cardiovascular Research 20:
588-596, 1986.
5. Ethier,C.R., Kamm,R.D., Palaszewski,B.A., Johnson,M. and Richardson,T.M.:
Calculations of flow resistance in the
juxtacanalicular meshwork. Investigative Ophthalmology and Visual Science
27: 1741-1750, 1986.
6. Johnson,M. and Kamm,R.D.: Numerical
studies of steady flow dispersion at low Dean number in a gently curving tube.
Journal of Fluid Mechanics 172: 329-345, 1986.
7. Johnson,M., Kamm,R., Ethier,C.R., and Pedley,T.: Scaling laws and the effects
of concentration polarization on the permeability of hyaluronic acid. Physicochemical
Hydrodynamics 9: 427-441, 1987.
8. Salzman,E.W., McManama,G.P., Shapiro,A.H., Robertson,L.K., Donovan,A.S.,
Blume,H.W., Sweeney,J., Kamm,R.D., Johnson,M. and Black,P.M.: Effect
of optimization of hemodynamics on fibrinolytic activity and antithrombotic
efficacy of external pneumatic compression. Annals of Surgery 206:
636-641, 1987.
9. Nguyen,K.P.V., Chung,M.L., Anderson,P.A., Johnson,M. and Epstein,D.L.:
Hydrogen Peroxide Removal by the Calf
Outflow Pathway. Investigative Ophthalmology and Visual Science 29:
976-981, 1988.
10. Johnson,M.: The enthralling world of SEM, Bulletin of the Boston Mycological
Club, 44,1: 3-4, 1988.
11. Ethier,C.R., Kamm,R.D., Johnson,M., Pavao,A.F. and Anderson,P.J.:
Further studies on the flow of aqueous humor through microporous filters.
Investigative Ophthalmology and Visual Science
30: 739-745, 1989.
12. Pavao,A.F., Lee,D.A., Ethier,C.R., Johnson,M., Anderson,P.J. and Epstein,D.L.:
Two dimensional gel electrophoresis of
calf aqueous humor, serum and filter-bound proteins. Investigative
Ophthalmology and Visual Science 30: 731-738, 1989.
13. Rosenquist, R., Epstein,D.L., Melamed,S., Johnson,M. and Grant,W.M.: Outflow
resistance of enucleated human Eyes at two different perfusion pressures and
different extents of trabeculotomy, Current Eye Research 8:
1233, 1989.
14. Johnson,M, Johnson,D.H., Kamm,R.D., deKater,A.W. and Epstein,D.:
The filtration characteristics of the aqueous outflow system, Experimental
Eye Research 50: 407-418, 1990.
15. Johnson, M., Kamm, R., Ho,L.W., Shapiro,A. and Pedley,T.J.: The
nonlinear growth of surface tension-driven instabilities of a thin annular
film, Journal of Fluid Mechanics, 233: 141 156, 1991.
16. Johnson,M., Chen,A., Epstein,D.L. and Kamm,R.D.: The
pressure and volume dependence of the rate of wash-out in the bovine eye,
Current Eye Research 10: 373-375, 1991.
17. Kim,A., Wang,C., Johnson,M. and Kamm,R.D.: The
specific hydraulic conductivity of bovine serum albumin, Biorheology,
11: 401-419, 1991.
18. Johnson,M., Shapiro,A., Ethier,C.R. and Kamm,R.D.: The
modulation of outflow resistance by the pores of the inner wall endothelium,
Investigative Ophthalmology and Visual Science 33:
1670-1675, 1992.
19. Murphy,C.G., Johnson,M. and Alvarado,J.: The
juxtacanalicular tissue in pigmentary glaucoma: the hydrodynamic role of pigment
and other constituents, Archives of Ophthalmology 110: 1779-1785, 1992.
20. Gong,H., Freddo,T.F. and Johnson,M.: Age-related
changes of sulfated proteoglycans in the normal trabecular meshwork, Experimental
Eye Research 55: 691-709, 1992.
21. Otis,D., Johnson,M. and Kamm,R.D.:
The role of pulmonary surfactant in airway closure: a computational study,
Journal of Applied Physiology 75: 1323-1333, 1993.
22. Johnson,M., Gong,H., Freddo,T.F., Ritter,N. and Kamm,R.D.: Serum
proteins generate aqueous outflow resistance in bovine eyes, Investigative
Ophthalmology and Visual Science 34: 3549-3557,
1993.
23. Otis,D.R. Jr., Ingenito,E.P., Kamm,R.D. and Johnson,M.:
Dynamic surface tension of TA surfactant: experiments and theory, Journal
of Applied Physiology 77: 2681-2688, 1994.
24. Brown, C.T., Vural, M., Johnson, M. and Trinkaus-Randall, V.:
Age-related changes of scleral hydration and sulfated glycosaminoglycans,
Mechanisms of Aging and Development 77:
97-101, 1995.
25. Freddo, T.F., Kamm, R.D. and Johnson, M: Pathway of albumin into the anterior
chamber, Graefe's Arch. Clin. Exp. Ophthalmol. 233:
662-665, 1995 (letter to the editor).
26. Whale, M.D., Grodzinsky, A.J. and Johnson, M.: The
effect of aging and pressure on the specific hydraulic conductivity of the
aortic wall, Biorheology 33: 17-44, 1996.
27. Sit, A., Gong, H., Ritter, N., Freddo, T.F., Kamm, R.D. and Johnson, M.:
The role of soluble proteins in generating
aqueous outflow resistance in the bovine and human eye, Experimental
Eye Research 64:
813-821, 1997.
28. Sit, A.J., Coloma, F.M., Ethier, C.R. and Johnson, M.:
Factors affecting the pores of the inner wall endothelium of Schlemm's canal,
Investigative Ophthalmology and Visual Science
38: 1517-1525, 1997.
29. Hubbard, W.C., Johnson, M., Gong, H., Gabelt, B.T., Peterson, J.A., Sawhney,
R., Freddo,T.F. and Kaufman, P.L.: Intraocular
pressure and outflow facility are unchanged following acute and chronic intracameral
chondroitinase ABC and hyaluronidase in monkeys, Experimental Eye Research, 65: 177-190, 1997
30. Gong, H., Ye,W., Johnson,M., Kamm,R.D. and Freddo,T.F.: The
non-uniform distribution of albumin in human and bovine cornea, Experimental
Eye Research, 65: 747-756, 1997.
31. Ye, W., Gong, H., Sit, A., Johnson, M. and Freddo, TF:
Interendothelial junctions in normal human Schlemm's canal respond to changes
in pressure, Investigative Ophthalmology and Visual Science, 38:
2460-2468, 1997.
32. Johnson, M. and Habyarimana, J.: An
operational test for distinguishing between complicated and chaotic behavior
in deterministic systems, Physica D, 116: 289-300, 1998.
33. Ethier, C.R., Sit, A.J., Coloma, F.M., and Johnson, M.: Two
populations of pores of the inner wall endothelium of Schlemm's canal,
Investigative Ophthalmology and Visual Science 39:
2041-2048, 1998.
34. Ingenito, E.P., Mark, L., Morris, J., Espinosa, F. F., Kamm,R.D. and Johnson,
M.: Biophysical characterization of
lung surfactant components, Journal of Applied Physiology 86: 1702-1714,
1999.
35. Johnson, M.: Education of our leaders in the next century, MIT Faculty
Newsletter, April/May 2000.
36. Johnson, M. and Tarbell, J.M.: A
biphasic, anisotropic model of the aortic wall, Journal of Biomechanical
Engineering 123:
52-57, 2001.
37. Morris, J., Ingenito, E.P., Mark, L., Kamm, R.D. and Johnson, M.: Dynamic
behavior of lung surfactant, Journal of Biomechanical Engineeringg 123: 106-113, 2001.
38. Johnson, D. and Johnson, M.: How
does non-penetrating glaucoma surgery work?, Journal of Glaucoma, 10:55-67,
2001.
39. Russell, P., Tamm, E.R., Grehn, F.J., Picht, G., and Johnson, M.:
The presence and properties of myocilin in the aqueous humor, Investigative
Ophthalmology and Visual Science 42: 983-986, 2001.
40. Overby, D., Ruberti, J., Gong, H., Freddo, T.F. and Johnson, M.:
Specific hydraulic conductivity of corneal stroma as seen by quick-freeze/deep-etch,
Journal of Biomechanical Engineering 123:
154-161, 2001.
41. Johnson, D.H. and Johnson, M.:
Aqueous outflow and glaucoma surgery, Ophthalmo-Chirurgie 13: 88-89, 2001.
42. Johnson, D.H. and Johnson, M.: Glaucoma
surgery and aqueous outflow: How does non-penetrating glaucoma surgery work?,
Archives of Ophthalmology 120: 67-70, 2001.
43. Johnson, M., Christensen, C., Sit, A., Chen, D., Read, T. and Ethier,
C.R. Glaucomatous eyes have
a reduced pore density in the inner wall endothelium of Schlemm's canal,
Investigative Ophthalmology and Visual Science 43:2950-2955,
2002
44. Gong, H., Overby, D., Ruberti, J., Johnson,M. and Freddo, T.: A
new view of the human trabecular meshwork using quick-freeze/deep-etch,
Experimental Eye Research 75: 347-358, 2002.
45. Overby, D., Gong, H., Freddo, T.F. and Johnson,M.: The mechanism of increasing
outflow facility during washout in the bovine eye, Investigative Ophthalmology
and Visual Science 43:
3455-3464, 2002.
46. Ruberti, J.W., Curcio, C.A., Millican, L., Menco, B.Ph.M., Huang, J.-D.,
and Johnson, M.: Quick-freeze/deep-etch
visualization of age-related lipid accumulation in Bruch's membrane, Investigative
Ophthalmology and Visual Science 44: 1753-1759, 2003.
47. Johnson, M.: Aqueous outflow resistance (debate summary), International
Glaucoma Review 4-3, 446-447, 2003.
48. Ethier, CR, Johnson, M. and Ruberti, J: Ocular
Biomechanics and Biotransport, Annual Review of Biomedical Engineering
(invited review article), 6:249-73 2004.
49. Seurynck, S.L., Brown, N.J., Wu, C.W., Germino, K.W., Kohlmeir,
E.K., Ingenito, E.P., Glucksberg, M.R., Barron, A.E. and Johnson, M.: Optical
monitoring of bubble size and shape in a pulsating bubble surfactometer,
Journal of Applied Physiology 99: 624-633, 2005.
50. Overby, D and Johnson, M.: A stereologic theory to correct for depth-of-field
effects in microscopy, The Journal of Microscopy, Vol 220, 176-189, 2005.
51. Johnson, M.: "What controls aqueous humour outflow resistance?", Experimental Eye Research 82: 545-557, 2006.
52. Johnson, M., Dabholkar, A., Huang, J., Presley J.B., Chimento M.F. and Curcio, C.A.: Comparison of Morphology of Human Macular and Peripheral Bruch's Membrane in Older Eyes, Current Eye Research 32: 791-799, 2007.
53. Huang, J., Presley J.B., Chimento M.F., Curcio, C.A. and Johnson, M.: Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch, Experimental Eye Research 85: 202-218, 2007.
Internal
Publications
The Effect
of GAGases on Outflow Facility in the Bovine Eye
Political Newsletters (personal)
Pre Newsletter:
Starwars
Newsletter
1: The Homeless; Abortion
Newsletter
2: Drugs
Newsletter
3: Foreign Policy
Newsletter
4: Tsongas; Nuclear Energy
Newsletter
5: Primaries/Elections; Human Intelligence; Aging
Newsletter
6: State Lotteries; Free Will and God; Human Intelligence; Lemonade
Newsletter
7: Hiroshima; Political Parties in Primaries; IX Amendment; Holiday Recipes
Newsletter
8: Affirmative Action; Government Efficiency; Wild Recipes
Newsletter
9: Education of Leaders, Multiple Universes, and Gun, Germs and Steel
Northwestern University Biomedical Engineering Department
1 Sept 2005